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Radafaxine hydrochloride

CAS No. 106083-71-0

Radafaxine hydrochloride( GW-353162 | BW-306U )

Catalog No. M10270 CAS No. 106083-71-0

A potent metabolite of bupropion; selectivly inhibits the reuptake of norepinephrine over dopamine; DAT and NET transporters inhibitor, and nAChR family modulator.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Radafaxine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent metabolite of bupropion; selectivly inhibits the reuptake of norepinephrine over dopamine; DAT and NET transporters inhibitor, and nAChR family modulator.
  • Description
    A potent metabolite of bupropion; selectivly inhibits the reuptake of norepinephrine over dopamine; DAT and NET transporters inhibitor, and nAChR family modulator. Depression Approved.
  • In Vitro
    The relatively low potency of Radafaxine hydrochloride (GW-353162A) in blocking DAT and its slow blockade suggests that it is unlikely to have reinforcing effects.
  • In Vivo
    ——
  • Synonyms
    GW-353162 | BW-306U
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Monoamine Transporter
  • Recptor
    Monoamine Transporter
  • Research Area
    Neurological Disease
  • Indication
    Depression

Chemical Information

  • CAS Number
    106083-71-0
  • Formula Weight
    292.2014
  • Molecular Formula
    C13H19Cl2NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 38 mg/mL
  • SMILES
    CC1C(OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O.Cl
  • Chemical Name
    2-Morpholinol, 2-(3-chlorophenyl)-3,5,5-trimethyl-, hydrochloride (1:1), (2S,3S)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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